1-Bromo-3-chloropropane CAS No.:109-70-6

1-Bromo-3-chloropropane CAS No.:109-70-6

1. Introduction of 1-Bromo-3-chloropropane 1-Bromo-3-chloropropane, with the CAS registry number of 109-70-6, is also named as 1,3-Chlorbromopropane. The product's categories are Organics; Bromo Chloro; Omega-Functional Alkanols, Carboxylic Acids, Amines & Halides; Omega-Haloalkyl...

Product Details

Name

1-Bromo-3-chloropropane

EINECS

203-697-1

CAS No.

109-70-6

Density

1.534 g/cm3

Solubility

insoluble in water

Melting Point

-59 °C

Formula

C3H6BrCl

Boiling Point

136.4 °C at 760 mmHg

Molecular Weight

157.44 .

Flash Point

38 °C

Transport Information


Appearance

clear liquid

Safety

16-45-36/37/39-26

Risk Codes

10-22-36/37/38-20/21/22

Molecular Structure

1.jpg

Hazard Symbols

5(001).jpgXn

Synonyms

1-bromo-3-chloro-propane;Propane,1-bromo-3-chloro-;1,3-Chbp;.omega.-Chlorobromopropane;1-Chloro-3-bromopropane;Trimethylene bromide chloride;1,3-Chlorbromopropane;1-Bromo-3-chloropropane [UN2688] [Poison];Trimethylene chlorobromide;l-Chloro-3-bromopropane;3-Bromo-1-chloropropane;3-Chloropropyl bromide;Propane, 1-bromo-3-chloro-;omega-Chlorobromopropane;3-Bromopropyl chloride;3-Chloro-1-bromopropane;1-Bromo-3-Chloropropane / BCP;1-Bromo-3-Chloropane;




1. Introduction of 1-Bromo-3-chloropropane

1-Bromo-3-chloropropane, with the CAS registry number of 109-70-6, is also named as 1,3-Chlorbromopropane. The product's categories are Organics; Bromo Chloro; Omega-Functional Alkanols, Carboxylic Acids, Amines & Halides; Omega-Haloalkyl Chlorides. Besides, it should be stored in a cool and well-ventilated place. 1-Bromo-3-chloropropane is used for organic synthesis and pharmaceutical industry and it is also used as a pharmaceutical intermediate.


2. Properties of 1-Bromo-3-chloropropane

Physical properties about 1-Bromo-3-chloropropane are: (1)ACD/LogP: 2.18; (2)ACD/LogD (pH 5.5): 2.18; (3)ACD/LogD (pH 7.4): 2.18; (4)ACD/BCF (pH 5.5): 26.67; (5)ACD/BCF (pH 7.4): 26.67; (6)ACD/KOC (pH 5.5): 365.08; (7)ACD/KOC (pH 7.4): 365.08; (8)#Freely Rotating Bonds: 2; (9)Index of Refraction: 1.468; (10)Molar Refractivity: 28.52 cm3; (11)Molar Volume: 102.6 cm3; (12)Polarizability: 11.3×10-24cm3; (13)Surface Tension: 30.9 dyne/cm; (14)Density: 1.534 g/cm3; (15)Flash Point: 38 °C; (16)Enthalpy of Vaporization: 35.84 kJ/mol; (17)Boiling Point: 136.4 °C at 760 mmHg; (18)Vapour Pressure: 9.15 mmHg at 25°C.


3. Structure Descriptors of 1-Bromo-3-chloropropane

(1)SMILES: BrCCCCl

(2)InChI: InChI=1/C3H6BrCl/c4-2-1-3-5/h1-3H2 

(3)InChIKey: MFESCIUQSIBMSM-UHFFFAOYAL

(4)Std. InChI: InChI=1S/C3H6BrCl/c4-2-1-3-5/h1-3H2 

(5)Std. InChIKey: MFESCIUQSIBMSM-UHFFFAOYSA-N


4. Toxicity of 1-Bromo-3-chloropropane

Organism

Test Type

Route

Reported Dose (Normalized Dose)

Effect

Source

mouse

LCLo

inhalation

7270mg/m3/2H (7270mg/m3)


"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 35, 1982.

mouse

LD50

oral

1290mg/kg (1290mg/kg)


"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 35, 1982.

rat

LC50

inhalation

5668mg/m3(5668mg/m3)


Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(9), Pg. 36, 1975.

rat

LD50

oral

930mg/kg (930mg/kg)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: MUSCLE WEAKNESS

Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 12, Pg. 93, 1971.


5. Preparation of 1-Bromo-3-chloropropane 

1-Bromo-3-chloropropane can be prepared by α-allyl chloride and hydrogen bromide.


6.Uses of 1-Bromo-3-chloropropane

1-Bromo-3-chloropropane can be used to produce (3-chloro-propoxy)-benzene. It will need reagent methanol. The yield is about 90%.

1.jpg


7. Other details of 1-Bromo-3-chloropropane

When you are using this chemical, please be cautious about it as the following:

It is flammable and harmful by inhalation, in contact with skin and if swallowed. Please keep away from sources of ignition - No smoking. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable gloves and eye/face protection. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).


Inquiry